The glymphatic system, glymphatic clearance pathway or paravascular system is an organ system for metabolic waste removal in the central nervous system (CNS) of vertebrates.

Oct 6, 2025 · The glymphatic system is a pathway that clears waste from your brain while you sleep. Like your lymphatic system, it uses fluid to wash away anything your brain doesn’t need.

The glymphatic system is a recently discovered macroscopic waste clearance system that utilizes a unique system of perivascular tunnels, formed by astroglial cells, to promote efficient elimination of …

Jun 21, 2019 · The glymphatic system, which runs parallel to arteries, also harnesses the pulsing of blood in circulation to help keep things moving.

Dec 11, 2025 · It's called the glymphatic system, and it is a network of fluid pathways that helps clear waste, toxins, and by-products from your brain. When this system runs smoothly, it protects memory, …

Oct 25, 2021 · The glymphatic system is a network of tunnel-like perivascular spaces that promotes directional, bulk fluid movement through the brain (Figure 1).

This 'peri-vascular' route for CSF-ISF exchange constitutes a complete anatomical pathway, which we dubbed the glymphatic system due to its dependence on glial cells performing a 'lymphatic' cleansing …

Feb 12, 2025 · The glymphatic system theory introduces a new perspective on fluid flow and homeostasis in the brain. Here, cerebrospinal fluid and interstitial fluid (CSF-ISF) moves from the …

5 days ago · Dysfunction of the glymphatic system (GS), a brain-wide waste clearance pathway dependent on polarized aquaporin-4 (AQP4) water channels on astrocytic endfeet, is increasingly …

Jun 1, 2023 · The glymphatic system is responsible for maintaining homeostasis within the central nervous system, including nutrient delivery, waste clearance, and consistency of the ionic …