Running back Christian McCaffrey and left tackle Trent Williams won't be on the practice field for the 49ers on Tuesday.

Trent Williams, Darnell Washington and Geno Smith were among the NFL players injured in Week 17. Injured players will be evaluated this week.

Trent Williams is one of the best linemen in modern NFL history, and the Sooner great suffered an injury on Sunday Night Football.

But it’s not all good news for the 49ers. Left tackle Trent Williams was shaken up on the first play from scrimmage — Purdy’s pick-six — and is questionable to return with a hamstring injury. Austen Pleasants came in to replace him.

“You get comfortable and start playing together better. … I don’t think anybody was too worried.”

Preview the player prop betting lines, stats and more for Christian McCaffrey before his San Francisco 49ers play the Seattle Seahawks in a Week 18 NFL

San Francisco 49ers running back Christian McCaffrey has had a remarkable season, which included him moving into ninth in 49ers rushing yards.