By far the most impressive feat of the San Francisco 49ers win over the Chicago Bears was that they were able to score 42 points without Trent Williams in the lineup. The star left tackle is usually the engine of the offense, but he left the game with a hamstring injury after Brock Purdy threw an opening pick-six.

Trent Williams in Week 18 vs. Seahawks as San Francisco fights for the NFC West title and No. 1 playoff seed at Levi's Stadium.

NFL Week 17 injury roundup highlights Amon-Ra St. Brown, Trent Williams, and critical injuries that could reshape NFL playoff picture.

One area in which the backup-heavy 49ers struggled early in the season was the run game. McCaffrey averaged fewer than three yards per carry through the first few weeks and couldn’t break any big gains. The offense had to lean on him as a pass catcher, not as a runner.

Trent Williams, Darnell Washington and Geno Smith were among the NFL players injured in Week 17. Injured players will be evaluated this week.

LT Trent Williams admitted his long-time touchdown dream has “faded” after a bizarre Titans moment, as San Francisco heads to the Colts.

Left tackle Austen Pleasants filled in admirably for Trent Williams and may need to do it against Seattle as well.

Trent Williams is one of the best linemen in modern NFL history, and the Sooner great suffered an injury on Sunday Night Football.