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Annual Reports

CIRM’s annual publications are filled with rich stories that highlight the work to accelerate world class science on behalf of all Californians. In each annual report, you can trace our history of ...
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Researcher Resources

CIRM provides funding across all stages of research, from basic science to translational studies and clinical trials. This support drives best-in-class research aimed at developing innovative ...
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Public Meetings

Get the latest CIRM news, information on upcoming meetings, and funding opportunities delivered to your inbox.
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Funding Opportunities

At the California Institute for Regenerative Medicine (CIRM), we are committed to the continued funding of groundbreaking research in regenerative medicine. To reflect this commitment, we are ...
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DISC5 Awards

The mission of the California Institute for Regenerative Medicine (CIRM) is to accelerate world class science to deliver transformative regenerative medicine treatments in an equitable manner to a ...
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CIRM awards $27 million to launch novel program designed to bring cell and gene therapies to underserved California communities

South San Francisco, Calif., October 30, 2025 – The California Institute for Regenerative Medicine (CIRM) has approved awarding $27 million through three grants across the state to create a network of ...
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CIRM approves $73 million in awards for discovery research

South San Francisco, CA, September 25, 2025 – The California Institute for Regenerative Medicine (CIRM) has approved awarding more than $73 million across 23 grants to support discovery research ...
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酪氨酸激酶和 BCL6 信号传导双重靶向根除白血病干细胞

慢性粒细胞白血病 (CML) 由致癌的 BCR-ABL1 酪氨酸激酶诱发，使用酪氨酸激酶抑制剂 (TKI) 可以有效治疗多年。 然而，除非CML患者接受终生TKI治疗，否则白血病最终会复发； 这是由于 TKI 治疗未能 ...
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CIRM awards $4.7 million for vision loss gene therapy

South San Francisco, CA, May 29, 2025 – The California Institute for Regenerative Medicine (CIRM), one of the world’s largest institutions dedicated to regenerative medicine, awarded $4.7 million to ...
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防止成纤维细胞中的 Engrailed-1 激活可以实现伤口再生而不留疤痕。

不留疤痕的再生 成年哺乳动物的伤口通常通过形成纤维化疤痕来愈合。 马斯卡拉克等人。 发现特定的皮肤成纤维细胞群（Engrailed-1 谱系阴性成纤维细胞）激活 Engrailed-1 的表达并开启促纤维化 ...
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Stem Cell and Genetic Research

When most people think about about stem cells treating disease they think of a stem cell transplant. In a stem cell transplant, stem cells are first specialized into the necessary adult cell type.
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CIRM awards $8 million to advance vision loss gene therapy to clinical trials

South San Francisco, CA, April 24, 2025 — The California Institute for Regenerative Medicine (CIRM), one of the world’s largest institutions dedicated to regenerative medicine, has approved awarding ...