Triglia discusses her research at the intersection of genetics, epigenetics, single-cell genomics and computational biology.

Using CRISPR, researchers have modelled the different developmental stages of childhood leukaemia. They discovered that ...

Analysis of proteins is not simple. Unlike DNA, there is incredible diversity in the concentration and variety of proteins created by a cell at any given moment. In our Proteomics Playbook we outline ...

As advancements in genetic technologies accelerate at an astonishing pace, the potential for gene editing to transform our world becomes closer to being realised. With the advent of revolutionary ...

Illumina’s systems employ short-read sequencing techniques, which has been the predominant NGS technology for the last decade. The company has made huge advances in the NGS space and now markets a ...

The field of genetics is a relatively young science, beginning with Gregor Mendel’s studies on the inheritance of traits in pea plants. The term “genetic engineering” was first coined by Jack ...

This feature was written using content from out recenty published Proteomics Playbook, which you can download for FREE here. The sequence of a protein is critical as it largely dictates the protein’s ...

Is science in the throes of a “reproducibility crisis”? If someone followed the same methods, techniques, and reagents as your experiment, would they have the same results? This describes the core ...

The idea that the experiences of our ancestors shape who we are today is not a novel one. In fact, throughout history, great thinkers from around the world have proposed theories and ideas to explain ...

Single-cell transcriptomics, or scRNA-seq, is widely used for analysing the transcriptome of single-cell populations. With scRNA-seq, gene expression profiling can explore genotype-phenotype ...

“Strange is this little animal, because of its exceptional and strange morphology and because it closely resembles a bear en miniature. That is the reason why I decided to call it little water bear.” ...

Written by Arpita Kulkarni (Director of the Functional Genomics and Bioinformatics Core at HMS/BIDMC). Across the life sciences, a quiet anxiety is growing: what is the role of the experimental ...