Philip Rivers starts again when he takes on the ferocious 49ers on "Monday Night Football." Here's score, highlights, stats ...

Who is playing on Monday Night Football? Check out the complete MNF game schedule, including Rams vs Falcons matchup for NFL ...

Brock Purdy, who threw a career-high five touchdowns, and the 49ers pulled away from the Colts on Monday night for a 48-27 ...

Joe Montana was the last 49ers quarterback to throw five touchdowns when he did it in 1990.The 49ers improved to 11-4 with a ...

Why Colts are wearing a black helmet with special uniforms on Monday Night Football originally appeared on The Sporting News.

Now back as the wily super-veteran, Rivers is pulling out all the tricks. And on this one, it worked to give the Colts an ...

San Francisco 49ers QB Brock Purdy notches his fifth TD of the night as he finds RB Christian McCaffrey for the score.

The Arizona Cardinals held a top-five draft position for all of 24 hours before Monday Night Football pushed them down the ...

USA Today's NFL experts make their picks for a Week 17 showdown between the Atlanta Falcons and Los Angeles Rams ...

The 49ers dealt a devastating blow to the Colts' playoff hopes on Monday night and there was plenty of blame to go around in ...

Indianapolis Colts host the San Francisco 49ers for NFL Monday Night Football tonight in Week 16. MNF time, TV schedule, how ...

Brock Purdy and Philip Rivers go toe-to-toe in what should be an entertaining tilt at Lucas Oil Stadium this Monday night.