A vanishingly rare genetic glitch in a single enzyme can erase a newborn’s brain cells in a matter of weeks, leaving doctors with almost no way to intervene. Researchers have now traced that ...

Life may have emerged from a surprisingly simple network of chemical reactions long before cells or genes existed.

Scientists have traced a devastating pattern of brain cell loss in a handful of families to a single, ultra-rare mutation ...

Scientists build a synthetic metabolism that converts CO2-derived formate into valuable chemicals outside living cells.

Four billion years ago, Earth was violent, hot, and unstable. Yet new research suggests that by then, life had already ...

AlphaFold didn't accelerate biology by running faster experiments. It changed the engineering assumptions behind protein ...

Alcohol consumption leads to the formation of a toxic compound called acetaldehyde, which damages DNA. A research team from ...

Scientists have identified a small flaw in the enzyme GPX4 that prevents neurons from defending themselves. This mutation, ...

University of California San Diego researchers have discovered the enzyme responsible for chromothripsis, a process in which ...

UC San Diego scientists discover enzyme responsible for scrambling cancer genomes; results could enable new treatments for ...

University of California San Diego researchers have discovered the enzyme responsible for chromothripsis, a process in which a single chromosome is shattered into pieces and rearranged in a scrambled ...

RFdiffusion2, RFdiffusion3, and Riff-Diff each solve different structural problems in computational enzyme design ...