WEST LAFAYETTE, Ind. — Researchers at Purdue University just made high-throughput screening, a process often used in drug discovery, 10 times faster than previous methods. “The area of high-throughput ...
The most important resource and most consumed food worldwide is drinking water. International and national regulations and norms regulate quality control for drinking water. For instance, the Method ...
Alanine (Ala) scanning is a widely used mutagenesis approach in which residues in a target protein are systematically substituted for alanine at selected positions by site-directed mutagenesis, ...
Single-cell multiomics provides a comprehensive view of the cellular heterogeneity and the complex interplay between multiple layers of cellular omics, namely genome, epigenome, transcriptome, and ...
Mineral oil hydrocarbons (MOH) are extensively utilized as lubricants and may contain mutagenic and carcinogenic impurities. Therefore, food safety authorities mandate testing ingredients, finished ...
High-performance liquid chromatography-mass spectrometry (HPLC-MS) combines the separation power of LC with the detection specificity of MS. It has become an indispensable analytical tool in the ...
One of the major tasks in present-day biology is to map the chromosomal positions of nucleosomes, TFs, chromatin remodeling enzymes, histone modifications, polymerases and chaperones. Genome-wide ...
HTS assays need to be robust, reproducible and sensitive. 12, 13 Assays utilized in HTS also need to be validated for their biological and pharmacological relevance. These methods should be ...
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