This important study provides a detailed analysis of the transcriptional landscape of the mouse hippocampus in the context of various physiological states. The main conclusions have solid support: ...

Cirtuvivint is a selective pan-CLK, pan-DYRK inhibitor that modulates alternative RNA splicing, including transcripts involved in oncogenic pathways. Preclinical studies have shown that CLK/DYRK ...

Scientists at St. Jude Children's Research Hospital have characterized a hidden intermediate state at the center of Src kinase function. This hidden state allows the kinase to repeatedly modify its ...

Humans have it. So does Drosophila. But not yeast. That "it" is a small pause at the start of gene activity—a brief molecular halt that may have helped life evolve from simple cells to complex animals ...

A negative mindset and emotional turmoil can cause a person to spiral, even in the comfort of their own home. Unfortunately, ...

Collier’s landfill, east of Great Wolf Lodge and north of Picayune Strand, receives daily loads that are spread and buried.

Scientists at St. Jude Children's Research Hospital have characterized a hidden intermediate state at the center of Src ...

Stress and broken sleep do not just leave people groggy, they quietly chip away at the very immune cells that keep infections ...

A study by the Mildred Scheel Early Career Center group led by Dr. Mohamed Elgendy at the TUD Faculty of Medicine provides ...

Plants form a critical model for understanding regulated cell death (RCD) as part of their sophisticated immune responses. In the ongoing evolutionary arms ...

Triglia discusses her research at the intersection of genetics, epigenetics, single-cell genomics and computational biology.