eLife

Intersection of transient cell states with stable cell types in hippocampus

This important study provides a detailed analysis of the transcriptional landscape of the mouse hippocampus in the context of various physiological states. The main conclusions have solid support: ...

Scientists build virtual tissue tools to map how cells talk in disease

Scientists at Duke-NUS Medical School have developed two powerful computational tools that could transform how researchers ...

Stripe patterns in blood cells offer new clues for diagnosing disorders and understanding natural designs

Stripe patterns are commonly seen in nature—for instance, birds and fish move in coordinated flocks and schools, fingerprints ...
Frontiers

Understanding regulated cell death in plant immunity: From molecular mechanisms to evolutionary insights

Plants form a critical model for understanding regulated cell death (RCD) as part of their sophisticated immune responses. In the ongoing evolutionary arms ...
eLife

Voltage imaging reveals the emergence of population activity in the spinal cord

This paper presents an important advance in genetically encoded voltage imaging of the developing zebrafish spinal cord in vivo, capturing voltage dynamics in neuronal populations, single cells, and ...
Gut

Twenty-four-week anti-PD-1 antibody regimen promoted HBsAg reduction and concurrently enhanced HBV-specific T cell responses in patients with chronic hepatitis B

Background PD-1 blockade has emerged as a promising approach for functional cure of chronic hepatitis B (CHB). Objective This study aimed to evaluate the safety profile of anti-PD-1 antibody (αPD-1), ...