Left tackle Austen Pleasants filled in admirably for Trent Williams and may need to do it against Seattle as well.

The thread running through this improbable season features an unstoppable 49ers offense and the defense making a game-saving ...

Several questions begin to arise as the 49ers' starting tackle, Trent Williams, exits Monday's game with an injury.

Pro Bowl left tackle Trent Williams left the San Francisco 49ers' game against the Chicago Bears on Sunday night after ...

One area in which the backup-heavy 49ers struggled early in the season was the run game. McCaffrey averaged fewer than three ...

San Francisco won 42-38 against the Bears, but the offense’s performance without Williams in this matchup was a key ...

The San Francisco 49ers caught a tough injury break involving left tackle Trent Williams during a big game against the ...

Trent Williams, Darnell Washington and Geno Smith were among the NFL players injured in Week 17. Injured players will be ...

Typically, when Williams leaves the game, the chances of the 49ers winning are over. The 49ers were just 4-11 when Williams ...

But it’s not all good news for the 49ers. Left tackle Trent Williams was shaken up on the first play from scrimmage — Purdy’s ...

Trent Williams' return to the San Francisco 49ers game is questionable after the All-Pro suffered a hamstring injury on the ...

Williams (hamstring) has been ruled out for the rest of Sunday night's contest against the Bears. Williams sustained a hamstring injury in the early moments of the first quarter, and his night has now ...