With the No. 1 seed at stake, the status of multiple 49ers Pro Bowlers is unclear for Saturday's showdown against the ...

The San Francisco 49ers are preparing for their Week 18 contest against the Seattle Seahawks on Saturday at Levi's Stadium in ...

The San Francisco 49ers practiced Tuesday without two key pieces of their offense, running back Christian McCaffrey and left ...

The San Francisco 49ers are dealing with multiple significant injury concerns entering their Week 18 showdown against the ...

The 49ers have won six games in a row. And if they win just one more, they'll get the No. 1 seed and a first-round bye in the ...

The San Francisco 49ers have dealt with several key injuries throughout the 2025 season. And yet, this Saturday against the ...

Running back Christian McCaffrey and left tackle Trent Williams won't be on the practice field for the 49ers on Tuesday.

Kyle Shanahan dropped ominous injury updates on Tuesday. Find out how the team is planning to make it work against the ...

The Seahawks remain on top of this week's power rankings, but they have to play the red-hot 49ers for the NFC West title ...

NFL Week 17 injury roundup highlights Amon-Ra St. Brown, Trent Williams, and critical injuries that could reshape NFL playoff ...

Left tackle Austen Pleasants filled in admirably for Trent Williams and may need to do it against Seattle as well.

Trent Williams in Week 18 vs. Seahawks as San Francisco fights for the NFC West title and No. 1 playoff seed at Levi's ...