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Annual Reports

CIRM’s annual publications are filled with rich stories that highlight the work to accelerate world class science on behalf of all Californians. In each annual report, you can trace our history of ...
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Researcher Resources

CIRM provides funding across all stages of research, from basic science to translational studies and clinical trials. This support drives best-in-class research aimed at developing innovative ...
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Public Meetings

Get the latest CIRM news, information on upcoming meetings, and funding opportunities delivered to your inbox.
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Funding Opportunities

At the California Institute for Regenerative Medicine (CIRM), we are committed to the continued funding of groundbreaking research in regenerative medicine. To reflect this commitment, we are ...
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DISC5 Awards

The mission of the California Institute for Regenerative Medicine (CIRM) is to accelerate world class science to deliver transformative regenerative medicine treatments in an equitable manner to a ...
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CIRM awards $27 million to launch novel program designed to bring cell and gene therapies to underserved California communities

South San Francisco, Calif., October 30, 2025 – The California Institute for Regenerative Medicine (CIRM) has approved awarding $27 million through three grants across the state to create a network of ...
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CIRM approves $73 million in awards for discovery research

South San Francisco, CA, September 25, 2025 – The California Institute for Regenerative Medicine (CIRM) has approved awarding more than $73 million across 23 grants to support discovery research ...
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CIRM awards $4.7 million for vision loss gene therapy

South San Francisco, CA, May 29, 2025 – The California Institute for Regenerative Medicine (CIRM), one of the world’s largest institutions dedicated to regenerative medicine, awarded $4.7 million to ...
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Stem Cell and Genetic Research

When most people think about about stem cells treating disease they think of a stem cell transplant. In a stem cell transplant, stem cells are first specialized into the necessary adult cell type.
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CIRM awards $8 million to advance vision loss gene therapy to clinical trials

South San Francisco, CA, April 24, 2025 — The California Institute for Regenerative Medicine (CIRM), one of the world’s largest institutions dedicated to regenerative medicine, has approved awarding ...
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人类新皮质外室下区的神经源性放射状胶质细胞。

发育中的啮齿动物皮层中的神经元是由充当神经干细胞的放射状胶质细胞产生的。这些上皮细胞排列在脑室中并产生中间祖细胞，这些细胞迁移到脑室下区（SVZ）并增殖以增加神经元数量。
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剪接因子 TRA2B 是神经祖细胞存活所必需的。

前体 mRNA 的选择性剪接可以快速调节大量蛋白质的表达。 RNA 结合蛋白 TRA2B (SFRS10) 在果蝇性别分化过程中发育调节的选择性剪接中发挥着明确的作用。 TRA2B 对于哺乳动物胚胎发生也是必需的 ...