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Annual Reports

CIRM’s annual publications are filled with rich stories that highlight the work to accelerate world class science on behalf of all Californians. In each annual report, you can trace our history of ...
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Researcher Resources

CIRM provides funding across all stages of research, from basic science to translational studies and clinical trials. This support drives best-in-class research aimed at developing innovative ...
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Minutia, Inc.

Foundation – Discovery Stage Research Projects Katy Digovich Immune cloaking of human stem cell-derived insulin-producing cells for curative cell therapy without immunosuppression $1,192,586 Quest – ...
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DNA methylation-dependent and -independent binding of CDX2 directs activation of distinct developmental and homeostatic genes.

uring development, our organs form correctly only if the right genes turn on in the right cells at the right times. Special proteins called transcription factors help control this process by attaching ...
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Conserved lipid metabolic reprogramming confers hypoxic and aging resilience.

Wei I Jiang, Goncalo Dias do Vale, Quentinn Pearce, Kaitlyn Kong, Wenbin Zhou, Jeffrey G McDonald, James E Cox, Neel S Singhal, Dengke K Ma The Arctic ground squirrel (AGS, Urocitellus parryii), an ...
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Pervasive and programmed nucleosome distortion patterns on single mammalian chromatin fibers.

Marty G Yang, Hannah J Richter, Simai Wang, Colin P McNally, Nicole Harris, Simaron Dhillon, Michela Maresca, Elzo de Wit, Holger Willenbring, Jacquelyn Maher, Hani Goodarzi, Vijay Ramani We present a ...
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Clinical Trial Stage Projects

The mission of California Institute for Regenerative Medicine (CIRM) is to accelerate stem cell treatments to patients with unmet medical needs. With our Clinical Stage Programs, we intend to speed up ...
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从人类多能干细胞系中高效生成造血前体和祖细胞。

通过模仿造血系统的胚胎发育，我们开发了一种优化的体外分化方案，用于从人胚胎干细胞（ES）和诱导多能干细胞（iPS）生成造血谱系前体和原始造血细胞。 在七种不同的人类 ES 和 iPS 系上 ...
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Stem Cell-Based Cartilage Tissue Regeneration

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Protocol to study ductal progenitor-like cells from the adult human pancreas using 3D suspension and methylcellulose-based culture systems.

The pancreas is comprised of two compartments, the exocrine and endocrine. The exocrine acinar cells produces and secreted digestive enzymes that are carried by ductal cells to the duodenum, whereas ...
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Maria Mirotsou

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Corrélation entre l'existence des palissades de Vogt et l'épaisseur épithéliale limbique dans le déficit en cellules souches limbiques.

CONTEXTE : Les objectifs de l'étude étaient d'étudier l'épaisseur épithéliale limbique chez des sujets présentant un déficit en cellules souches limbiques et d'évaluer la corrélation entre les ...