The 49ers added insult to injury with a game-sealing pick-six, all but ending the Colts' playoff hopes. Indianapolis has now ...

The San Francisco 49ers extended their winning streak to four games with a 37-24 victory over the Tennessee Titans on Sunday.

The 49ers quarterback debate isn't really a debate. Brock Purdy's play, stats, and wins make the case—while Mac Jones shines as the NFL's best backup.

The 49ers were without Ricky Pearsall on Monday, but their star tight end picked up the slack with his first 100-yard receiving game of ...

After two touchdown drives from Indianapolis Colts quarterback Philip Rivers to start the game, 49ers defensive coordinator ...

The San Francisco 49ers may have to navigate a couple of games without one of their superstars, but he avoided a longer-term ...

Week 16 was a great week for the San Francisco 49ers, who clinched a playoff berth and moved up in both the division and ...

NFL.com breaks down the playoff-clinching scenarios for Week 17 of the 2025 NFL..

The 49ers may have offensive tackle Trent Williams around for longer than expected after his comments following their win ...

How did the Jaguars' upset of the Broncos shake up the AFC postseason picture? Which teams have the best odds to catch the ...

The San Francisco 49ers had six players make the NFC roster for the 2026 Pro Bowl Games, but one more should've ...

The 49ers clinched a playoff spot before they took the field on Monday night, but that didn't take any wind out of their sails against the Colts.