With six receptions and 146 yards from scrimmage, McCaffrey registered his 54th career game with at least five receptions and ...

The San Francisco 49ers delivered a statement performance under the lights in Indianapolis, rolling past the Colts with a ...

FB Kyle Juszczyk, TE George Kittle, RB Christian McCaffrey, T Trent Williams, LB Luke Gifford, and LS Jon Weeks were selected ...

The San Francisco 49ers entered Monday night having already clinched a playoff berth, but their win in Indy reflected a team ...

Get an inside view of the 49ers locker room following the team's Week 16 win over the Colts presented by Ticketmaster.

San Francisco 49ers QB Brock Purdy, TE George Kittle, RB Christian McCaffrey, T Trent Williams, and LB Dee Winters ...

San Francisco 49ers QB Brock Purdy surprised families with incredible holiday gifts, including Toyota vehicles, Rivalries ...

San Francisco 49ers RB Christian McCaffrey catches a 2-yard touchdown pass from QB Brock Purdy in the team's Week 16 matchup ...

San Francisco 49ers DL C.J. West reflected on his first-career sack and shared his reaction to the 49ers "Monday Night ...

San Francisco 49ers RB Christian McCaffrey catches a 9-yard touchdown pass from QB Brock Purdy, marking his second TD of the ...

The Detroit Lions loss to the Pittsburgh Steelers on Sunday secured San Francisco's place in the NFC playoff field with three ...

San Francisco 49ers QB Brock Purdy completed a 23-yard pass to WR Skyy Moore in the team's Week 16 matchup. San Francisco ...