The San Francisco 49ers won't play until Sunday night in Week 17, but other games throughout the week could impact their ideal finish to the season.

QB Brock Purdy rewards his offensive line with custom Rolex watches for Christmas as San Francisco pushes toward the NFC West title and NFL playoffs.

Philip Rivers starts again when he takes on the ferocious 49ers on "Monday Night Football." Here's score, highlights, stats and more for Colts-49ers.

The San Francisco 49ers have been one of the most injured teams thoughout the entire 2025 season. While the team will never get completely healthy, it is signif

Where do the 49ers rank in Week 17 power rankings after their blowout win over the Colts? See how national media views San Francisco's surge.

Here's how to watch the Bears this Sunday, as they return to primetime against a contending San Francisco 49ers team.

Here are your top 49ers storylines for Wednesday, December 24th:

The San Francisco 49ers beat the Indianapolis Colts 48-27, led by Brock Purdy’s 5 TDs. Colin Cowherd asks if the now 11-4 49ers are serious title contenders.

The 49ers are coming off a win over the Titans following their bye week, their fourth consecutive win after a loss to the Rams had dropped them to 6-4 on the year. The playoff-bound Niners got another massive favor from the Seahawks on Thursday night, and they now control their own destiny in the race for the No. 1 seed in the NFC.

Philip Rivers, the grandfather and former Pro Football Hall of Fame semifinalist, came out of retirement to play for the Indianapolis Colts.

The 49ers have a shot at the division crown and the No. 1 seed in the NFC but George Kittle remains sidelined by an ankle injury.