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Monday Night Football schedule, TV channel, time, streaming information for San Francisco 49ers vs Indianapolis Colts NFL Week 16 game Dec. 22, 2025.
Brock Purdy, who threw a career-high five touchdowns, and the 49ers pulled away from the Colts on Monday night for a 48-27 win.
San Francisco aims to improve playoff position while Indianapolis fights for postseason hopes with Philip Rivers at quarterback. Here's how to watch for free.
With a mini-bye week following their loss to the Seattle Seahawks last Thursday night, the Los Angeles Rams move forward with another primetime matchup, this ti
Joe Montana was the last 49ers quarterback to throw five touchdowns when he did it in 1990.The 49ers improved to 11-4 with a fifth consecutive win. The Colts fell to 8-7, with their loss clinching playoff berths for the Bills,
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NFL DFS, 49ers vs. Colts: Optimal daily Fantasy picks, lineup advice for 'Monday Night Football'
Daily Fantasy multimillionaire Mike McClure reveals his daily Fantasy football picks for Indianapolis vs. San Francisco on 'MNF'
Phillip Rivers leads the Indianapolis Colts against Brock Purdy and the San Francisco 49ers tonight in this NFL Week 16 showdown.
How to watch, listen to and live stream the Rams' Week 17 Monday Night Football matchup against the Atlanta Falcons on Dec. 29.
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