This study reports an important and novel finding that TENT5A, an enzyme involved in fine-tuning poly(A) tail length on selected mRNAs, is required for proper enamel mineralization in mice. The ...

Oxford Nanopore Technologies plc ( ONTTF) Q4 2025 Earnings Call March 2, 2026 5:45 AM EST Good morning, everyone, and thank you for joining us today. Before we move into the 2025 results presentation, ...

In recent years, mRNA in lipid nanoparticles (mRNA–LNPs) has emerged as a promising strategy for treating numerous conditions ...

Integrating AI with advanced robotics to create self-driving labs (SDL) is a promising approach to tackling molecular discovery. A new SDL system, called LUMI-lab, combines large-scale molecular ...

Naked mRNA administration in the testes rescues sperm function, demonstrating a potential therapeutic approach for genetic male infertility.

In an experimental trial, a personalized mRNA vaccine was tested in 14 individuals with an aggressive form of breast cancer. It trained immune cells to target cancer-specific mutant proteins, inducing ...

Advanced analytics and artificial intelligence (AI) will help make mRNA vaccines and therapeutics better by allowing biopharma engineers to fine-tune the enzymes used to manufacture such products.

In summer 2025, the SARS-CoV-2 JN.1 sublineage became dominant with more resistant variants, such as XFG, LP.8.1, and NB.1.8.1. COVID-19 mRNA boosters were therefore updated for the 2025–2026 season ...

Background Gut microbiota dysbiosis is linked to autism spectrum disorder (ASD) in children. However, the role of bacterial ...

BACKGROUND: The entrance of naive T cells into lymph nodes (LNs) is a crucial step for induction of heart transplant acceptance under costimulatory blockade. Specialized blood vessels within the LN ...