He might not win NFL Coach of the Year, but he’ll just have to settle for being the NFL’s best coach — by a significant ...

Other 49ers inactives include wide receiver Jordan Watkins, defensive lineman Robert Beal Jr., running back Isaac Guerendo, ...

One area in which the backup-heavy 49ers struggled early in the season was the run game. McCaffrey averaged fewer than three ...

The San Francisco 49ers received tough news on tight end George Kittle for Sunday's game against the Chicago Bears.

San Francisco 49ers head coach Kyle Shanahan provided the latest injury update on superstar tight end George Kittle ahead of ...

Tight end George Kittle and wide receiver Ricky Pearsall are questionable for the 49ers’ game Sunday night against the ...

George Kittle’s injured ankle forced him to miss practice again on Thursday, leaving the 49ers’ Pro Bowl tight end’s status ...

The most difficult matchups confronting the Bears this week includes on that might not come off because of 49ers injury.

The 49ers had three players deal with injuries on Monday night against the Colts. Here's what Kyle Shanahan said about those ...

Latest updates after 49ers tight end George Kittle suffered an ankle injury on "Monday Night Football" vs. the Colts Week 16.

Kyle Shanahan praised his defense for stopping the Bears' fourth-quarter comeback attempt on Sunday Night Football.

San Francisco 49ers head coach Kyle Shanahan compares the Chicago Bears balanced, play-action-driven attack to the 49ers own ...