He might not win NFL Coach of the Year, but he’ll just have to settle for being the NFL’s best coach — by a significant ...

The San Francisco 49ers lost starting left tackle Trent Williams to a hamstring injury, but it's unclear how much time he'll ...

Other 49ers inactives include wide receiver Jordan Watkins, defensive lineman Robert Beal Jr., running back Isaac Guerendo, ...

One area in which the backup-heavy 49ers struggled early in the season was the run game. McCaffrey averaged fewer than three ...

The San Francisco 49ers received tough news on tight end George Kittle for Sunday's game against the Chicago Bears.

San Francisco 49ers head coach Kyle Shanahan provided the latest injury update on superstar tight end George Kittle ahead of ...

Tight end George Kittle and wide receiver Ricky Pearsall are questionable for the 49ers’ game Sunday night against the ...

The San Francisco 49ers may have one of their top offensive weapons available after an injury took him out of Week 16.

George Kittle’s injured ankle forced him to miss practice again on Thursday, leaving the 49ers’ Pro Bowl tight end’s status ...

The most difficult matchups confronting the Bears this week includes on that might not come off because of 49ers injury.

Is George Kittle out for the season? When is George Kittle coming back? The latest George Kittle injury update and fantasy ...

Take a look at players who have been ruled out for the San Francisco 49ers Week 17 "Sunday Night Football" matchup versus the ...