6 Arthritis Research UK Primary Care Centre, Research Institute for Primary Care & Health Sciences and Keele Clinical Trials Unit, Keele University, Staffordshire, UK The need for pain to be avoided ...

FIFA Medical Assessment and Research Centre, and Schulthess Clinic, Zürich, Switzerland Correspondence to Mario Bizzini, FIFA Medical Assessment and Research Centre, FIFA-Strasse 20, P.O. Box, 8044 ...

Background: Depression negatively affects how a person feels, thinks, or behaves; is associated with impaired functioning in social and work settings; and can be associated with thoughts of suicide.

A 39-year-old man presented to the emergency department with left forearm pain after a fall during a motorcycle accident, in which he landed on an outstretched, pronated hand. Physical examination ...

Background Intrahepatic cholangiocarcinoma (iCCA) is a highly aggressive biliary tract cancer with a poor prognosis and a complex tumour microenvironment (TME) that remains poorly understood.

Background The JAK/STAT pathway plays a pivotal role in hepatic ischaemia/reperfusion (I/R) injury, a serious perioperative complication. Although signal transducers and activators of transcription 1 ...

Background Socioeconomic status (SES) is a potentially important upstream determinant of late-life cognitive health, but a review which captures the dynamic influence of SES across the life-course is ...

Background Endovascular thrombectomy achieves macroreperfusion in large vessel occlusion (LVO) stroke, but only one-quarter of patients had excellent functional outcome. Adjunct intra-arterial (IA) ...

Importance/background The 12-lead ECG is recommended in clinical guidelines for prehospital assessment of patients with suspected acute coronary syndrome (ACS) presenting to Emergency Medical Services ...

Objective To assess evidence of overall survival (OS) benefits of cancer drugs listed in China’s National Reimbursement Drug List (NRDL), the guiding standard for public insurance coverage of drugs ...

Objectives Body image dissatisfaction (BID) is relatively common in Chinese female undergraduates. This study aims to explore the reasons for BID among female undergraduates to develop effective early ...

Objectives Colon and rectum cancer, the third most common cancer globally, is a considerable health challenge worldwide. Despite the excellent insights offered by the global burden of disease (GBD) ...