Drug discovery requires two separate steps: checking whether a drug can bind to a harmful molecule or its receptor, and ...
In biology, many RNA molecules act as sophisticated microscopic machines. Among them, riboswitches function as tiny biological sensors, changing their 3D shape upon binding to a specific metabolite.
Figure 1: Solution structure of the rNedd4 WWIII–rENaC βP2 peptide complex. Based on the Nedd4, dystrophin and Pin1 WW domain complexes, two of which involve PY motif-containing ligands with different ...
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