As the immune system weakens with age, researchers have found a way to temporarily boost its function by reprogramming liver cells to support T-cell development.

A new drug may slow progression of -- and even reverse -- symptoms of a rare form of amyotrophic lateral sclerosis, or ALS, a ...

Craif Inc. in Nagoya, Japan, working with Nagoya University's Institute of Innovation for Future Society, has developed a ...

This article explores how single-cell multiomics and spatial transcriptomics are illuminating early pregnancy, uncovering ...

A study published in Engineering shows that a protein called U2 small nuclear RNA auxiliary factor 1 (U2AF1), released by ...

Cirtuvivint is a selective pan-CLK, pan-DYRK inhibitor that modulates alternative RNA splicing, including transcripts involved in oncogenic pathways. Preclinical studies have shown that CLK/DYRK ...

In this article, we examine ongoing challenges shaping target-based drug discovery and highlight how new technologies and interdisciplinary approaches are helping to address them.

A relatively mundane middle-aged rite of passage — shingles vaccination — might offer an added benefit: protection against, or even the slowing of the progression of, dementia.

Researchers at the Massachusetts Institute of Technology and Stanford University have reported a novel immunotherapy strategy that targets sugar-based immune checkpoints on tumour cells, with the ...

Triglia discusses her research at the intersection of genetics, epigenetics, single-cell genomics and computational biology.

One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...