SMRTS, a smart mRNA system, enables cell‑selective gene expression, expanding the mRNA toolbox for precision cancer therapies.

Researchers at the Icahn School of Medicine at Mount Sinai have developed a first-of-its-kind mRNA system that switches on therapeutic genes preferentially inside targeted cells—an advance ...

No matter where cancer cells grow in the human body, they are a threat to our health and our lives. But instead of treating them with chemotherapy or radiation - which have undesirable side effects - ...

New data highlight liver-encoded delivery of immune modulators as a strategy to mitigate age-related immune dysfunction.

As people age, their immune system function declines. T cell populations become smaller and can't react to pathogens as ...

Researchers at the Icahn School of Medicine at Mount Sinai have developed a first-of-its-kind mRNA system that switches on therapeutic genes preferentially inside targeted cells-an advance ...

MIT and Broad Institute researchers have developed an mRNA approach that temporarily programs liver cells to produce ...

As the immune system weakens with age, researchers have found a way to temporarily boost its function by reprogramming liver cells to support T-cell development.

Stanford Medicine investigators have unearthed the biological process by which mRNA-based vaccines for COVID-19 can cause ...

Researchers at MIT and the Broad Institute have found a way to overcome age-related immune system decline by temporarily programming cells in the liver to take over a critical immune system function: ...