New 3D genome maps reveal how DNA folding controls gene activity, offering fresh clues into disease and cell function.

A new study shows, for the first time, how the human genome folds and moves in 3D over time to control when genes turn on and ...

One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...

Although it also performs some functions in men, estrogen, the main female sex hormone, is involved in a myriad of processes, ...

In a landmark effort to understand how the physical structure of our DNA influences human biology, Northwestern investigators ...

A team of researchers has generated one of the most detailed 3D maps of human chromosomes, cataloging over 140,000 DNA looping interactions.

Study finds CRISPR/Cas gene editing causes “chromatin fatigue” – another surprise mechanism by which it can produce unwanted ...

AI maps fleeting DNA quadruplexes, revealing paired structures that control genes in healthy cells and cancer.

In a study published in Genome Research, a team of researchers, including Cornell College Assistant Professor of Biology ...

The rapid expansion of high-throughput sequencing technologies has generated unprecedented amounts of multi-omics data, ...

A tiny percentage of our DNA—around 2%—contains 20,000-odd genes. The remaining 98%—long known as the non-coding genome, or ...