AI maps fleeting DNA quadruplexes, revealing paired structures that control genes in healthy cells and cancer.

These sequences are extremely prone to mutations and rank among the most functionally important regions in the entire human ...

Triglia discusses her research at the intersection of genetics, epigenetics, single-cell genomics and computational biology.

Deep in coastal mangroves and even inside our own mouths, biologists are finding that DNA does not always sit in a simple ...

Humans have it. So does Drosophila. But not yeast. That "it" is a small pause at the start of gene activity - a brief molecular halt that may have ...

Penn State researchers discovered that two proteins within the CCR4-NOT complex have opposing effects on mRNA stability.

A newly revealed molecular tug-of-war may have implications for better understanding how a multitude of diseases and ...

Analyzing stochastic cell-to-cell variability can potentially reveal causal interactions in gene regulatory networks.

Iron is vital but toxic when free, so organisms store it in proteins like ferritin. This study in frogs showed ferritin gene ...

A newly discovered promoter element "start" points to a shared regulatory syntax for controlling transcription initiation in ...

With a snip of a gene, doctors may one day permanently lower dangerously high cholesterol, possibly removing the need for medication, according to a new pilot study published Saturday in the New ...