Let's update our NFL Power Rankings ahead of Week 17. We also looked at the best rookies from all 32..... 49ers Notebook: Dee ...

The 49ers just beat the Indianapolis Colts 48-27 and won their 11th game of the season. Last season, they lost 11 games.

The 49ers scored on their first four possessions of the first half, taking a 24-17 lead into the locker room at halftime.San Francisco had touchdown drives ...

Purdy is the first Niners quarterback to throw five touchdown passes in a game since Steve..

The 49ers on Monday night did what they had to do to keep their hopes of the No. 1 seed alive.The offense did most of the ...

San Francisco 49ers head coach Kyle Shanahan talks to the media after Week 16 win against the Indianapolis Colts about goals ...

Brock Purdy and the 49ers turned it up a notch against the Colts to close out Week 16, despite having already clinched a ...

The San Francisco 49ers finished their Week 16 "Monday Night Football" contest with a 48-27 win over the Indianapolis Colts ...

The 49ers had three players deal with injuries on Monday night against the Colts. Here's what Kyle Shanahan said about ...

The San Francisco 49ers were healthy in the first quarter against the the Indianapolis Colts, but the injuries are piling up ...

The San Francisco 49ers may win their Week 16 matchup with the Indianapolis Colts, but they lost one of their best players to ...

The San Francisco 49ers are headed to Indianapolis for a Week 16 matchup against the Colts, and they now officially know who ...