The application of Bayesian methods to large-scale phylogenetics problems is increasingly limited by computational issues, motivating the development of methods that can complement existing Markov ...

The increasing interest in Bayesian group sequential design is due to its potential to reinforce efficiency in clinical trials, shorten drug development time, and enhance the accuracy of statistical ...

We may take observations sequentially from a population with unknown mean θ. After this sampling stage, we are to decide whether θ is greater or less than a known constant ν. The net worth upon ...

The customary approach to early-phase clinical trial design, where the focus is on identification of the maximum tolerated dose, is not always suitable for noncytotoxic or other targeted therapies.

In the Big Data era, many scientific and engineering domains are producing massive data streams, with petabyte and exabyte scales becoming increasingly common. Besides the explosive growth in volume, ...