Contrary to a long-standing assumption that blood vessel cells in healthy tissues and those associated with tumors are similar, a new study unequivocally demonstrates that tumor blood vessel cells are ...

Abnormal tumor blood vessels promote cancer progression and treatment resistance. Researchers have developed two approaches to repair tumor blood vessels and they have devised a method to measure the ...

Researchers examine the local communication between endothelial cells and tumors cells and its effects on endothelial cell orientation. The approach uses co-cultured human umbilical vein endothelial ...

The leaky, disorganized mess of blood vessels that support tumors can stop drugs from reaching their targets and thereby nullify their impact. Recognizing that, researchers have identified a way to ...

Targeting and customizing blood vessels in tumors to increase T cell infiltration and maintain their function may represent the next breakthrough in cancer therapy. The European Research Council has ...

Treatment resistance is a significant challenge in immunotherapy, but it is not fully understood. A recent review summarized 5 tumor microenvironment traits that may inhibit therapy effectiveness and ...

Transcript:Edward S. Kim, MD: For decades, we used 2-drug chemotherapy—that’s how we treated the majority of our lung cancer patients. Over time, we’ve tried many times to see if we can add more ...

Cancer is characterized by the uncontrolled replication of abnormal cells. It can affect almost any part of your body, including your blood vessels. Although cancer is often thought of as a human ...

Tumors can destroy the blood vessels of muscles even when the muscles are nowhere close to the tumor. That is the key finding of a new study that my colleagues and I recently published in the journal ...

Schematic drawing of a blood vessel around tumors before and after treatment with ABTAA. The picture above shows a typical tumor vasculature characterized by damaged walls, red blood cells leakage and ...