Telomerase is a specialized reverse transcriptase containing an intrinsic telomerase RNA (TR) which provides the template for telomeric DNA synthesis. Distinct from conventional reverse transcriptases ...

For the treatment of HIV infection, non-nucleoside reverse transcriptase inhibitors (NNRTIs) are used to prevent viral replication by binding to a pocket near the polymerase active site of HIV-1 ...

Scientists studied how the epigenetic landscape influences the binding of pioneer transcription factors, affecting access to DNA. Like thread tightly wrapped around a spool, DNA is wrapped around ...