Intracellular peptides, generated predominantly via the ubiquitin–proteasome system, have emerged as critical modulators of cell signalling. These peptides play multifaceted roles, ranging from ...

The recent discovery of glycoRNAs on the cell surface upended the world of cell biology. These glycoRNAs were found to form ...

A new paper published today in Cell highlights how researchers have leveraged AI-based computational protein design to create a novel synthetic ligand that activates the Notch signaling pathway, a key ...

A paper published in Cell highlights how researchers have leveraged AI-based computational protein design to create a novel synthetic ligand that activates the Notch signaling pathway, a key driver in ...

In recent years, scientists have begun to reveal the myriad ways that gut microbes can impact our health; they had identified ...

Common gut bacteria use protein delivery systems to interact directly with human cells, reshaping how scientists view the microbiome.

An international research team has succeeded in deciphering a key mechanism that controls the growth of pancreatic cancers.

Johns Hopkins scientists reveal that “inactive” GluD brain proteins regulate neuronal communication and open up new ...

Researchers at Johns Hopkins Medicine say they unexpectedly found new information about a protein's special role in getting brain cells to communicate at the right time and place in experiments with ...

The structural and functional characteristics of mitochondria shape their role as signaling organelles, with far-reaching ...

Study findings map out a new way in which antiviral signals engage with cellular metabolism to balance defense and repair.