SIRPα immunotherapy include targeting overexpressed CD47 in cancers to boost macrophage activity, using dual function molecules to enhance efficacy, and innovative drug designs reducing red blood cell ...
Membrane protein targeting and insertion is a fundamental process in cellular biology that ensures proteins are correctly delivered to, and integrated within, the lipid bilayer. Proteins destined for ...
Scientists have discovered a new way to advance drug discovery and diagnostics by targeting a part of the proteome (the complete set of proteins in an organism) that was previously thought ...
Targeted inhibition of a "signal jammer" protein may improve how tumors respond to immunotherapy. Published today in Nature, a new study demonstrates how some cancer cells use the protein ...
Morning Overview on MSN
Could attacking toxic protein chains finally slow neurodegenerative disease?
Researchers are testing a fundamentally different strategy against neurodegenerative disease: instead of clearing protein ...
Protein-Protein Interactions (PPIs) are critical for biological systems to function properly. Strong interactions maintain structural integrity and function, whereas weaker interactions enable ...
Targeting OTULIN has proven to eliminate toxic tau proteins in human neurons for the first time, opening a new avenue for treating dementia.
Researchers found that individuals have distinct baseline levels of brain-derived proteins in cerebrospinal fluid, masking ...
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