Interim Executive Director, Biodesign Institute Director, Biodesign Institute's Virginia G. Piper Center for Personalized Diagnostics; Virginia G. Piper Chair of Personalized Medicine; Pr ...

The field of proteomics has undergone rapid advancements over the last decade and protein microarrays have emerged as a promising technological platform for the challenging task of studying complex ...

A protein microarray consists of the immobilization of proteins in organized rows and columns upon a support structure. The structure of the protein microarray allows for high-throughput analysis of ...

A designed polypeptide scaffold contains a surface immobilization domain and a target capture domain for flexible protein arraying. 'Microarray' might just be the hottest buzzword in biology today.

Advances in material science combined with nanofabrication and computational design have led to the discovery of label-free protein microarray techniques. These techniques are of enormous benefit for ...

Better Tools and Methodologies Are Needed to Move the Field Past a Critical Stage Microarrays have advanced significantly over the years, which is a good thing as genomics would not exist if not for ...

Proteins are workhorses that carry out most of the biological functions in our cells. While the genes we inherit from our parents, our so-called genome, are fixed and usually remain unchanged ...

Protein microarrays are one aspect of highly automated, large-scale biological screening technologies, the other is nucleic acid arrays. As DNA arrays reveal their origin in Southern blotting ...

WEST LAFAYETTE, Ind. — A new algorithm makes interpreting the results of cryo-electron microscopy maps easier and more accurate, helping researchers to determine protein structures and potentially ...

*These authors contributed equally to the preparation of this manuscript. Cell-based technologies for printing protein microarrays are faced with poor protein expression, protein insolubility, ...

The sequencing phase of the human genome project is now near completion, but then what? An even harder challenge remains — to identify the structures and functions of all proteins encoded in the ...