Understanding human gene function in living organisms has long been hampered by fundamental differences between species.

Technologies at the Advanced Rodent Transgenics Laboratory include genome editing design and implementation and transgenic ...

Researchers at the Jan and Dan Duncan Neurological Research Institute (NRI) at Texas Children’s Hospital and Baylor College of Medicine recently made an important advance in neurodegenerative disease ...

In recent months, the Food and Drug Administration and National Institutes of Health have announced new initiatives to reduce and replace animal testing in biomedical research. Central to these ...

Researchers have developed a gene-editing treatment for prion disease that extends lifespan by about 50 percent in a mouse model of the fatal neurodegenerative condition. The treatment, which uses ...

Humanized mouse models are vital for studying human gene function, but fully replacing mouse genes with complete human ...