Zachary Gergely, Michele Jones, Bojun Zhou, Cai Cash, J. Richard McIntosh, and Meredith D. Betterton (2023). Distinct regions of the kinesin-5 C-terminal tail are essential for mitotic spindle midzone ...

This is a preview. Log in through your library . Abstract We have isolated a cold-sensitive allele of TUB2, the sole gene encoding β-tubulin in S. cerevisiae, that confers a specific defect in spindle ...

Cell division is essential to the propagation of life. During cell division, mitotic spindles segregate duplicated chromosomes with high fidelity. Spindle structure depends on the proper polar ...

RanGAP1 was the first documented substrate for conjugation with the ubiquitin-like protein SUMO-1. However, the functional significance of this conjugation has not been fully clarified. We sought to ...

No significant financial relationships to disclose. This is an ASCO Meeting Abstract from the 2007 ASCO Annual Meeting. This abstract does not include a full text component.

This is a fluorescence microscopy image of abnormal mitotic spindles in four breast cancer cells that were treated with antibody-linked maytansine. The chromosomes (blue) are not able to arrange in ...

Research achieves scientific breakthrough in understanding cell division. An international research collaboration, led by Prof. Dr. Robert Grosse (Centre for Integrative Biological Signalling Studies ...

For a new plant to grow from a seed, cells need to divide numerous times. Daughter cells can each take on different tasks and sometimes vary in size. How plants determine the plane of cell division in ...

For a new plant to grow from a seed, cells need to divide numerous times. Daughter cells can each take on different tasks and sometimes vary in size. How plants determine the plane of cell division in ...