Researchers from Karolinska Institutet have discovered how mammalian cells prevent the gradual buildup of harmful mutations in mitochondrial DNA, the small but vital genome that powers every cell. The ...

In most eukaryotes, the inheritance of mitochondrion and its DNA (mtDNA) is strictly maternal, despite the fact that a spermatozoon can inject up to 100 functional mitochondria into the oocyte during ...

Researchers report evidence of biparental inheritance of mitochondrial DNA. Mitochondria, the energy-producing organelles of cells, contain their own compact genomes that are separate from the nuclear ...

Scientists have argued whether or not the often-studied mitochondrial DNA molecule is clonally inherited. It is with assuming clonal inheritance this type of DNA has been used to track the origin of ...

Researchers at the Max Delbrück Center and the University of Oxford have found that a cellular housekeeping function called autophagy—by which cell components are broken down and recycled—plays a ...