This detailed overview explains the technical mechanisms of LC-MS proteomics, including peptide separation, ion generation, ...

Responding to a lack of sensitive analytical methods for detecting associated medications in complex wastewater matrices, ...

To detect estrogen and its metabolites in the ovarian-type stroma of pancreatic mucinous cystic neoplasm (MCN) tumors, researchers applied a novel liquid chromatography–tandem mass spectrometry (LC-MS ...

High-performance liquid chromatography-mass spectrometry (HPLC-MS) combines the separation power of LC with the detection specificity of MS. It has become an indispensable analytical tool in the ...

Master the principles of MS/MS in proteomics to improve peptide sequencing accuracy. This guide covers fragmentation methods, ...

The sample throughput of high-sensitivity liquid chromatography-mass spectrometry (LC-MS) based proteomics analysis is restricted by the pressure limitations of LC and column hardware, with some ...

Sample preparation plays a crucial role in bioanalytical analysis involving chromatography. Insufficient sample preparation, such as skipping protein precipitation, phospholipid removal (PLR), ...

Pharmaceutical Technology® spoke with Steve Lowes, senior director of Scientific Affairs at IQVIA Laboratories, ahead of AAPS PharmSci 360 to discuss how LC–MS is used in bioanalysis. The field of ...

New users of the LC/MS laboratory and Sample Preparation Lab are required to engage in hands-on orientation to facility operations (e.g., laboratory access, scheduling, general use of equipment, ...