Power and sample size calculations are critical parts of any research design for genetic association. We present a method that utilizes haplotype frequency information and average marker-marker ...

This protocol describes how to appropriately design a genetic association case–control study, either focusing on a candidate gene (CG) or region or implementing a genome-wide approach. The steps ...

This is a preview. Log in through your library . Abstract Small-sample properties of old and new odds ratio estimators are studied with regard to bias and mean ...

In a nationally representative sample of 1.1 million homes, we compared the prevalence of smoking among 33,000 deceased women and 41,000 deceased men (case subjects) with the prevalence of smoking ...