A single enzyme that can generate all four nucleoside triphosphates, the building blocks of ribonucleic acid (RNA), has been ...

CHAMPAIGN, Ill. — A new artificial intelligence-powered tool can help researchers determine how well an enzyme fits with a desired target, helping them find the best enzyme and substrate combination ...

The mechanism by which an enzyme used in industrial production of an important drug for type-2 diabetes recognizes its target has been demonstrated by a group of researchers. This finding will further ...

Using artificial intelligence, researchers show how γ-secretase recognizes substrates - an important advance for fundamental and translational research. The γ-secretase enzyme is capable of cleaving ...

A clever means of localizing and confining enzymes and the substrate molecules they bind with has been presented by researchers, speeding up reactions essential for life processes. Living systems rely ...

The contribution of enzymes as a biological catalyst in almost all processes occurring in live organisms is significant. Studying the enzyme reactions taking place in a system, individually, is ...

Chemists at MIT have introduced an engineered biosynthetic enzyme that accepts a wider range of substrates into periwinkle plant culture to make unnatural analogs of alkaloids (Nat. Chem. Biol., DOI: ...

It is well known in physics and chemistry that equal charges repel each other, while opposite charges attract. It was long assumed that this principle also applies when enzymes – the biological ...

Halogenated compounds are widespread in the pharmaceutical and agrochemical industries. But the reagents used to make them can produce hazardous waste and mixtures of compounds. Enzymes can provide a ...

Epigenetic drug discovery and development programs have attracted much attention and investment in recent years. This is driven by the potential to develop novel therapeutic strategies that can ...