Cell cycle checkpoint-related genes (CCCRGs) are implicated in the development and progression of hepatocellular carcinoma ...
Metabolism, far from being just a housekeeping function, underlies all changes in cell size and function ...
GMCL1-dependent degradation of 53BP1 suppresses mitotic surveillance, tuning p53 activation thresholds that govern cell fate decisions and cellular responses after mitosis.
Despite the immense amount of genetic material present in each cell, around 3 billion base pairs in humans, this material ...
Understanding why cancer cells rely on specific genes is critical for designing effective targeted therapies. A new study ...
By editing thousands of genes in mouse stem cells, the scientists identified a list of over 300 that are crucial for neural differentiation.
Researchers at The Institute of Cancer Research, London identified the CIP2A–TOPBP1 complex as a master regulator of DNA repair during mitosis, coordinating backup pathways that protect chromosomes ...
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