The novel method uses a recycling photoreactor with an immobilized photosensitizer, coupled with a high-performance liquid chromatography technology, to enable efficient and sustainable synthesis of Z ...

Reactions that completely break carbon-carbon double bonds have particular transformative power in synthesis. Ozonolysis, which splits one alkene into two carbonyl compounds using trioxygen, is widely ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, No. 23 (June 10, 2014), pp. 8368-8373 (6 pages) Despite recent advances of asymmetric synthesis, the ...

The group incorporated an N-heterocyclic carbene to the Ni catalyst, which is key in two ways. First, the carbene drives an efficient C-Ni addition across the alkene. “Second, because it is ...

Researchers have discovered a new way to drive chemical reactions that could generate a wide variety of azetidines -- four-membered nitrogen heterocycles that have desirable pharmaceutical properties.

Taking inspiration from enzymes, chemists have developed a catalyst to simplify the synthesis of ethers, key functional components of many drugs, foods, personal care items and other consumer goods.

It is well known that many of the Z-alkenes cannot be prepared through conventional methods involving thermodynamic methods, while photoisomerization can offer good yields. Photoisomerization is a ...