Adaptor protein (AP) complexes play central roles in intracellular vesicular trafficking by coupling cargo selection to ...

The tiny protein known as transthyretin can cause big problems in the body when it misfolds after secretion. While healthy transthyretin moves hormones through blood and spinal fluid, misfolded ...

Illustration showing how integrating protein three-dimensional structures with artificial intelligence algorithms can predict synergistic or antagonistic effects of drug combinations, guiding safer ...

The first full-length structures of two heat shock chaperone proteins in a complex reveal the key structural region regulating their function, according to a new study from St. Jude Children's ...

Protein engineering is a powerful biotechnological process that focuses on creating new enzymes or proteins and improving the functions of existing ones by manipulating their natural macromolecular ...

Proteins are among the most studied molecules in biology, yet new research shows they can still hold surprising secrets. Researchers have discovered previously undetected chemical bonds within ...