Trent Williams is one of the best linemen in modern NFL history, and the Sooner great suffered an injury on Sunday Night Football.

But it’s not all good news for the 49ers. Left tackle Trent Williams was shaken up on the first play from scrimmage — Purdy’s pick-six — and is questionable to return with a hamstring injury. Austen Pleasants came in to replace him.

“You get comfortable and start playing together better. … I don’t think anybody was too worried.”

The 49ers may have offensive tackle Trent Williams around for longer than expected after his comments following their win over the Colts.

San Francisco 49ers left tackle Trent Williams explained how the team has grown "closer together" throughout the 2025 NFL season.

Rosters for the 2026 Pro Bowl Games are set with the Seattle Seahawks, San Francisco 49ers, Denver Broncos and Baltimore Ravens leading the league with six selections apiece.

Devin McCourty and Mike Florio discuss Trent Williams’ comments on San Francisco 49ers quarterback Brock Purdy and react to the shades worn by the 11-time Pro Bowler.

The San Francisco 49ers lost starting left tackle Trent Williams to a hamstring injury, but it's unclear how much time he'll miss.