One area in which the backup-heavy 49ers struggled early in the season was the run game. McCaffrey averaged fewer than three yards per carry through the first few weeks and couldn’t break any big gains. The offense had to lean on him as a pass catcher, not as a runner.

Left tackle Austen Pleasants filled in admirably for Trent Williams and may need to do it against Seattle as well.

As the San Francisco 49ers push toward the final stretch of the season, veteran left tackle Trent Williams has made one thing clear: this year’s Super Bowl opportunity carries real weight. With Super Bowl LX looming, Williams believes the work being done now, especially up front, can define the team’s legacy.

Hours before kickoff at Levi's Stadium, the parking lots were already alive with music, barbecue smoke, and a sea of red jerseys as San Francisco 49ers fans soaked in the anticipation of a pivotal late-season matchup against the Chicago Bears.

The Chicago Bears are getting set to take on the San Francisco 49ers. These are the five players who must have eyes on them in this matchup.