The Patriots are marching into this matchup on a 10-game winning streak, which is tied for the third longest in team history. They are the first team in NFL history to win 10 consecutive games with at least 23 points scored and 23-or-less points allowed in each game.

Week 17 will have some key players dealing with injuries that may affect your Fantasy Football Championship game.

The Philadelphia Eagles come in as the NFC East champions, but the Buffalo Bills have work to do to retain their AFC East title when they host this NFL Week 17 matchup. The Eagles (10-5) hit a rough patch and went on a three-game losing skid because of an inconsistent offense but have bounced back to score 60 points in winning their past two games.

The New England Patriots (12-3) are just one Buffalo Bills (11-4) loss away from clinching the AFC East. Meanwhile, the Miami Dolphins (6-9) and New York Jets (3-12) are both eliminated from playoff contention and are already packing their bags for the offseason.

The Patriots enter the Week 17 matchup against the Jets as heavy favorites. New England, despite being the road team, is a 13.5-point betting favorite, according to CBS Sports. Both with the spread and straight up, all seven CBS experts pick the Patriots .

Our Patriots vs. Jets predictions, odds & expert picks for Sunday, December 28, 2025. Lay the points with the Pats.

Notable odds: The Colts are on the brink of elimination, with just a 2% shot at the playoffs, according to the Athletic, following Monday's loss to the 49ers. A Texans victory on Saturday vs. the Chargers will end the Colts' season.